Hi Team
Been struggling with this for the past week and not making much progress.
Was working perfectly as a Plex Server for a year with Win10 on it until I had to mess around with it 
Upgraded it to the latest Win10
Upgraded the BIOS of the Minix PC
Installed VNC Connect.
And things started to go wrong - essentially the unit disconnects from the network when using Plex to stream content. Plex is not reachable and neither is the unit on the local LAN......no IP Connectivity.
Or when using VNC and Plex simultaneously.
In order to bring it back - I either have to wait for a hour OR reboot the box. As a Plex server the unit is no longer functional as this defeats the purpose....
Plex has been setup correctly - reachable both internally and externally - so that is not the issue.
Connectivity is via Ethernet - 100MB FULL.
I have since
Fresh install W10
Downgraded from Win10 to Win8.1 with a fresh install twice.
Updated the drivers for graphics, Realtek USB
Reinstalled Plex numerous times
Firewall & Defender and OFF
Has anyone experienced similar issues before and if so how did you resolve them?
Once I get back home I will be able to access the logs and post them to assist with troubleshooting.